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C10958

Chemleader

Genipin

HPLC>98%

Product Name: Genipin

Synonyms: (+)-Genipin
CAS No.: 6902-77-8
Chemical Name: (1R,4aS,7aS)-methyl 1-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate;Methyl (1R,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate
Formula: C11H14O5
M.Wt: 226.23
EINECS Number: NA
MDL Number: MFCD00888600
Cat. No.-Pack Size Specification Sales Price(US$) Discounted Price(US$) Available Inventory Qty Ordered
C10958- 100mg 100mg 160.00 160.00 10
C10958- 500mg 500mg 380.00 380.00 10
C10958- 1g 1g 550.00 550.00 10
Appearance: White crystal powder
Specific Rotation: NA
Solubility: Soluble in DMSO, Ethanol, DMF Storage Condition: -20° C
Biological Activity:

Genipin is a compound isolated from Gardenis jasminoides Ellis fruits which acts as a cell permeable inhibitor of UCP2 (uncoupling protein 2). Increases glucose-stimulated insulin secretion, mitochondrial membrane potential and ATP levels in pancreatic island cells. Genipin has been shown to induce apoptosis and is a protein cross-linking agent. Genipin, at 5 μM, increases glucose-stimulated insulin secretion in isolated pancreatic islets chronically exposed to high levels of glucose. Genipin also exhibits anti-inflammatory and anti-angiogenic properties by inducing apoptosis in FaO rat hepatoma cells and human hepatocarcinoma Hep3B cells.

Sensitivity: NA
Density: ~1.4 g/cm3 (Predicted) Purity: HPLC>98%
Boiling Point: ~416.0 °C at 760 mmHg (Predicted) Flash Point: NA
Melting Point: 121-125 °C Refractive Index: n20D 1.57 (Predicted)